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- Title
BNArray: an R package for constructing gene regulatory networks from microarray data by using Bayesian network.
- Authors
Chen, Xiaohui; Chen, Ming; Ning, Kaida
- Abstract
BNArray is a systemized tool developed in R. It facilitates the construction of gene regulatory networks from DNA microarray data by using Bayesian network. Significant sub-modules of regulatory networks with high confidence are reconstructed by using our extended sub-network mining algorithm of directed graphs. BNArray can handle microarray datasets with missing data. To evaluate the statistical features of generated Bayesian networks, re-sampling procedures are utilized to yield collections of candidate 1st-order network sets for mining dense coherent sub-networks.
- Publication
Bioinformatics (Oxford, England), 2006, Vol 22, Issue 23, p2952
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btl491