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- Title
Additional gene ontology structure for improved biological reasoning.
- Authors
Myhre, Simen; Tveit, Henrik; Mollestad, Torulf; Laegreid, Astrid
- Abstract
The Gene Ontology (GO) is a widely used terminology for gene product characterization in, for example, interpretation of biology underlying microarray experiments. The current GO defines term relationships within each of the independent subontologies: molecular function, biological process and cellular component. However, it is evident that there also exist biological relationships between terms of different subontologies. Our aim was to connect the three subontologies to enable GO to cover more biological knowledge, enable a more consistent use of GO and provide new opportunities for biological reasoning.
- Publication
Bioinformatics (Oxford, England), 2006, Vol 22, Issue 16, p2020
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btl334