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Title
ACE-it: a tool for genome-wide integration of gene dosage and RNA expression data.
Authors
van Wieringen, Wessel N; Belien, Jeroen A M; Vosse, Sjoerd J; Achame, Eskeatnaf M; Ylstra, Bauke
Abstract
We describe a tool, called ACE-it (Array CGH Expression integration tool). ACE-it links the chromosomal position of the gene dosage measured by array CGH to the genes measured by the expression array. ACE-it uses this link to statistically test whether gene dosage affects RNA expression.