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- Title
Rosetta error model for gene expression analysis.
- Authors
Weng, Lee; Dai, Hongyue; Zhan, Yihui; He, Yudong; Stepaniants, Sergey B; Bassett, Douglas E
- Abstract
In microarray gene expression studies, the number of replicated microarrays is usually small because of cost and sample availability, resulting in unreliable variance estimation and thus unreliable statistical hypothesis tests. The unreliable variance estimation is further complicated by the fact that the technology-specific variance is intrinsically intensity-dependent.
- Publication
Bioinformatics (Oxford, England), 2006, Vol 22, Issue 9, p1111
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btl045