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- Title
Identification of plant microRNA homologs.
- Authors
Dezulian, Tobias; Remmert, Michael; Palatnik, Javier F; Weigel, Detlef; Huson, Daniel H
- Abstract
MicroRNAs (miRNAs) are a recently discovered class of non-coding RNAs that regulate gene and protein expression in plants and animals. MiRNAs have so far been identified mostly by specific cloning of small RNA molecules, complemented by computational methods. We present a computational identification approach that is able to identify candidate miRNA homologs in any set of sequences, given a query miRNA. The approach is based on a sequence similarity search step followed by a set of structural filters.
- Publication
Bioinformatics (Oxford, England), 2006, Vol 22, Issue 3, p359
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti802