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- Title
Large-scale prokaryotic gene prediction and comparison to genome annotation.
- Authors
Nielsen, Pernille; Krogh, Anders
- Abstract
Prokaryotic genomes are sequenced and annotated at an increasing rate. The methods of annotation vary between sequencing groups. It makes genome comparison difficult and may lead to propagation of errors when questionable assignments are adapted from one genome to another. Genome comparison either on a large or small scale would be facilitated by using a single standard for annotation, which incorporates a transparency of why an open reading frame (ORF) is considered to be a gene.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 24, p4322
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti701