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- Title
Structure clustering features on the Sfold Web server.
- Authors
Chan, Chi Yu; Lawrence, Charles E; Ding, Ye
- Abstract
The energy landscape of RNA secondary structures is often complex, and the Boltzmann-weighted ensemble usually contains distinct clusters. Furthermore, the minimum free energy structure often lies outside of the cluster containing the structure determined by comparative sequence analysis. We have developed procedures to characterize and visualize the Boltzmann-weighted ensemble, and have made them available on the Sfold Web server. The new features on the Web server include clustering statistics, ensemble and cluster centroids, multi-dimensional scaling display and energy landscape representation of the Boltzmann-weighted ensemble.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 20, p3926
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti632