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- Title
GenColors: accelerated comparative analysis and annotation of prokaryotic genomes at various stages of completeness.
- Authors
Romualdi, Alessandro; Siddiqui, Roman; Glöckner, Gernot; Lehmann, Rüdiger; Sühnel, Jürgen
- Abstract
GenColors is a new web-based software/database system aimed at an improved and accelerated annotation of prokaryotic genomes, considering information on related genomes and making extensive use of genome comparison. It offers a seamless integration of data from ongoing sequencing projects and annotated genomic sequences obtained from GenBank. The genome comparison tools determine, for example, best-bidirectional hits, gene conservation, syntenies and gene core sets. Swiss-Prot/TrEMBL hits allow annotations in an effective manner. To further support the annotation base-specific quality data can also be displayed if available. With GenColors dedicated genome browsers containing a group of related genomes can be easily set up and maintained. It has been efficiently used for Borrelia garinii and is currently applied to various ongoing genome projects.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 18, p3669
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti606