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- Title
Prediction of protein-protein interactions by combining structure and sequence conservation in protein interfaces.
- Authors
Aytuna, A Selim; Gursoy, Attila; Keskin, Ozlem
- Abstract
Elucidation of the full network of protein-protein interactions is crucial for understanding of the principles of biological systems and processes. Thus, there is a need for in silico methods for predicting interactions. We present a novel algorithm for automated prediction of protein-protein interactions that employs a unique bottom-up approach combining structure and sequence conservation in protein interfaces.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 12, p2850
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti443