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- Title
Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary.
- Authors
Mao, Xizeng; Cai, Tao; Olyarchuk, John G; Wei, Liping
- Abstract
High-throughput technologies such as DNA sequencing and microarrays have created the need for automated annotation of large sets of genes, including whole genomes, and automated identification of pathways. Ontologies, such as the popular Gene Ontology (GO), provide a common controlled vocabulary for these types of automated analysis. Yet, while GO offers tremendous value, it also has certain limitations such as the lack of direct association with pathways.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 19, p3787
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti430