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Title
An algorithm for identification of bacterial selenocysteine insertion sequence elements and selenoprotein genes.
Authors
Zhang, Yan; Gladyshev, Vadim N
Abstract
Incorporation of selenocysteine (Sec) into proteins in response to UGA codons requires a cis-acting RNA structure, Sec insertion sequence (SECIS) element. Whereas SECIS elements in Escherichia coli are well characterized, a bacterial SECIS consensus structure is lacking.