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- Title
Use of within-array replicate spots for assessing differential expression in microarray experiments.
- Authors
Smyth, Gordon K; Michaud, Joëlle; Scott, Hamish S
- Abstract
Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the resulting information. The usual practice is to average the duplicate or triplicate results for each probe before assessing differential expression. This results in the loss of valuable information about genewise variability.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 9, p2067
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti270