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- Title
Dynamic network reconstruction from gene expression data applied to immune response during bacterial infection.
- Authors
Guthke, Reinhard; Möller, Ulrich; Hoffmann, Martin; Thies, Frank; Töpfer, Susanne
- Abstract
The immune response to bacterial infection represents a complex network of dynamic gene and protein interactions. We present an optimized reverse engineering strategy aimed at a reconstruction of this kind of interaction networks. The proposed approach is based on both microarray data and available biological knowledge.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 8, p1626
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti226