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- Title
Boolean relationships among genes responsive to ionizing radiation in the NCI 60 ACDS.
- Authors
Pal, Ranadip; Datta, Aniruddha; Fornace, Albert J, Jr; Bittner, Michael L; Dougherty, Edward R
- Abstract
An early use of gene-expression data coming from microarrays was to discover non-linear multivariate intergene relationships. Pursuing this direction, the motivation for this paper is 2-fold: (1) to discover and elucidate multivariate logical predictive relations among gene expressions in a dataset arising from radiation studies using the NCI 60 Anti-Cancer Drug Screen (ACDS) cell lines; and (2) to demonstrate how these logical relations based on coarse quantization reflect corresponding relations in the continuous data.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 8, p1542
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti214