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- Title
An empirical Bayes approach to inferring large-scale gene association networks.
- Authors
Schäfer, Juliane; Strimmer, Korbinian
- Abstract
Genetic networks are often described statistically using graphical models (e.g. Bayesian networks). However, inferring the network structure offers a serious challenge in microarray analysis where the sample size is small compared to the number of considered genes. This renders many standard algorithms for graphical models inapplicable, and inferring genetic networks an 'ill-posed' inverse problem.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 6, p754
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti062