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- Title
An experimental evaluation of a loop versus a reference design for two-channel microarrays.
- Authors
Vinciotti, V; Khanin, R; D'Alimonte, D; Liu, X; Cattini, N; Hotchkiss, G; Bucca, G; de Jesus, O; Rasaiyaah, J; Smith, C P; Kellam, P; Wit, E
- Abstract
Despite theoretical arguments that so-called 'loop designs' for two-channel DNA microarray experiments are more efficient, biologists continue to use 'reference designs'. We describe two sets of microarray experiments with RNA from two different biological systems (TPA-stimulated mammalian cells and Streptomyces coelicolor). In each case, both a loop and a reference design were used with the same RNA preparations with the aim of studying their relative efficiency.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 4, p492
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bti022