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- Title
Outcome signature genes in breast cancer: is there a unique set?
- Authors
Ein-Dor, Liat; Kela, Itai; Getz, Gad; Givol, David; Domany, Eytan
- Abstract
Predicting the metastatic potential of primary malignant tissues has direct bearing on the choice of therapy. Several microarray studies yielded gene sets whose expression profiles successfully predicted survival. Nevertheless, the overlap between these gene sets is almost zero. Such small overlaps were observed also in other complex diseases, and the variables that could account for the differences had evoked a wide interest. One of the main open questions in this context is whether the disparity can be attributed only to trivial reasons such as different technologies, different patients and different types of analyses.
- Publication
Bioinformatics (Oxford, England), 2005, Vol 21, Issue 2, p171
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bth469