We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
SelSim: a program to simulate population genetic data with natural selection and recombination.
- Authors
Spencer, Chris C A; Coop, Graham
- Abstract
SelSim is a program for Monte Carlo simulation of DNA polymorphism data for a recombining region within which a single bi-allelic site has experienced natural selection. SelSim allows simulation from either a fully stochastic model of, or deterministic approximations to, natural selection within a coalescent framework. A number of different mutation models are available for simulating surrounding neutral variation. The package enables a detailed exploration of the effects of different models and strengths of selection on patterns of diversity. This provides a tool for the statistical analysis of both empirical data and methods designed to detect natural selection.
- Publication
Bioinformatics (Oxford, England), 2004, Vol 20, Issue 18, p3673
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bth417