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- Title
Breakpoint identification and smoothing of array comparative genomic hybridization data.
- Authors
Jong, Kees; Marchiori, Elena; Meijer, Gerrit; Vaart, A V D; Ylstra, Bauke
- Abstract
We describe a tool, called aCGH-Smooth, for the automated identification of breakpoints and smoothing of microarray comparative genomic hybridization (array CGH) data. aCGH-Smooth is written in visual C++, has a user-friendly interface including a visualization of the results and user-defined parameters adapting the performance of data smoothing and breakpoint recognition. aCGH-Smooth can handle array-CGH data generated by all array-CGH platforms: BAC, PAC, cosmid, cDNA and oligo CGH arrays. The tool has been successfully applied to real-life data.
- Publication
Bioinformatics (Oxford, England), 2004, Vol 20, Issue 18, p3636
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bth355