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- Title
DBRF-MEGN method: an algorithm for deducing minimum equivalent gene networks from large-scale gene expression profiles of gene deletion mutants.
- Authors
Kyoda, Koji; Baba, Kotaro; Onami, Shuichi; Kitano, Hiroaki
- Abstract
Large-scale gene expression profiles measured in gene deletion mutants are invaluable sources for identifying gene regulatory networks. Signed directed graph (SDG) is the most common representation of gene networks in genetics and cell biology. However, no practical procedure that deduces SDGs consistent with such profiles has been developed.
- Publication
Bioinformatics (Oxford, England), 2004, Vol 20, Issue 16, p2662
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bth306