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- Title
Pathway Miner: extracting gene association networks from molecular pathways for predicting the biological significance of gene expression microarray data.
- Authors
Pandey, Ritu; Guru, Raghavendra K; Mount, David W
- Abstract
We have developed a web-based system (Pathway Miner) for visualizing gene expression profiles in the context of biological pathways. Pathway Miner catalogs genes based on their role in metabolic, cellular and regulatory pathways. A Fisher exact test is provided as an option to rank pathways. The genes are mapped onto pathways and gene product association networks are extracted for genes that co-occur in pathways. The networks can be filtered for analysis based on user-selected options.
- Publication
Bioinformatics (Oxford, England), 2004, Vol 20, Issue 13, p2156
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bth215