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- Title
Growing genetic regulatory networks from seed genes.
- Authors
Hashimoto, Ronaldo F; Kim, Seungchan; Shmulevich, Ilya; Zhang, Wei; Bittner, Michael L; Dougherty, Edward R
- Abstract
A number of models have been proposed for genetic regulatory networks. In principle, a network may contain any number of genes, so long as data are available to make inferences about their relationships. Nevertheless, there are two important reasons why the size of a constructed network should be limited. Computationally and mathematically, it is more feasible to model and simulate a network with a small number of genes. In addition, it is more likely that a small set of genes maintains a specific core regulatory mechanism.
- Publication
Bioinformatics (Oxford, England), 2004, Vol 20, Issue 8, p1241
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bth074