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- Title
Alu repeat analysis in the complete human genome: trends and variations with respect to genomic composition.
- Authors
Grover, Deepak; Mukerji, Mitali; Bhatnagar, Pankaj; Kannan, K; Brahmachari, Samir K
- Abstract
Transposon-derived Alu repeats are exclusively associated with primate genomes. They have gained considerable importance in the recent times with evidence of their involvement in various aspects of gene regulation, e.g. alternative splicing, nucleosome positioning, CpG methylation, binding sites for transcription factors and hormone receptors, etc. The objective of this study is to investigate the factors that influence the distribution of Alu repeat elements in the human genome. Such analysis is expected to yield insights into various aspects of gene regulation in primates.
- Publication
Bioinformatics (Oxford, England), 2004, Vol 20, Issue 6, p813
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bth005