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- Title
A global test for groups of genes: testing association with a clinical outcome.
- Authors
Goeman, Jelle J; van de Geer, Sara A; de Kort, Floor; van Houwelingen, Hans C
- Abstract
This paper presents a global test to be used for the analysis of microarray data. Using this test it can be determined whether the global expression pattern of a group of genes is significantly related to some clinical outcome of interest. Groups of genes may be any size from a single gene to all genes on the chip (e.g. known pathways, specific areas of the genome or clusters from a cluster analysis).
- Publication
Bioinformatics (Oxford, England), 2004, Vol 20, Issue 1, p93
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btg382