We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A random variance model for detection of differential gene expression in small microarray experiments.
- Authors
Wright, George W; Simon, Richard M
- Abstract
Microarray techniques provide a valuable way of characterizing the molecular nature of disease. Unfortunately expense and limited specimen availability often lead to studies with small sample sizes. This makes accurate estimation of variability difficult, since variance estimates made on a gene by gene basis will have few degrees of freedom, and the assumption that all genes share equal variance is unlikely to be true.
- Publication
Bioinformatics (Oxford, England), 2003, Vol 19, Issue 18, p2448
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btg345