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- Title
Algorithms for large-scale genotyping microarrays.
- Authors
Liu, Wei-mn; Di, Xiaojun; Yang, Geoffrey; Matsuzaki, Hajime; Huang, Jing; Mei, Rui; Ryder, Thomas B; Webster, Teresa A; Dong, Shoulian; Liu, Guoying; Jones, Keith W; Kennedy, Giulia C; Kulp, David
- Abstract
Analysis of many thousands of single nucleotide polymorphisms (SNPs) across whole genome is crucial to efficiently map disease genes and understanding susceptibility to diseases, drug efficacy and side effects for different populations and individuals. High density oligonucleotide microarrays provide the possibility for such analysis with reasonable cost. Such analysis requires accurate, reliable methods for feature extraction, classification, statistical modeling and filtering.
- Publication
Bioinformatics (Oxford, England), 2003, Vol 19, Issue 18, p2397
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btg332