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- Title
Inferring strengths of protein-protein interactions from experimental data using linear programming.
- Authors
Hayashida, Morihiro; Ueda, Nobuhisa; Akutsu, Tatsuya
- Abstract
Several computational methods have been proposed for inference of protein-protein interactions. Most of the existing methods assume that protein-protein interaction data are given as binary data (i.e. whether or not each protein pair interacts). However, multiple biological experiments are performed for the same protein pairs and thus the ratio (strength) of the number of observed interactions to the number of experiments is available for each protein pair.
- Publication
Bioinformatics (Oxford, England), 2003, Vol 19 Suppl 2, pii58
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btg1061