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- Title
Using hidden Markov models to analyze gene expression time course data.
- Authors
Schliep, Alexander; Schönhuth, Alexander; Steinhoff, Christine
- Abstract
Cellular processes cause changes over time. Observing and measuring those changes over time allows insights into the how and why of regulation. The experimental platform for doing the appropriate large-scale experiments to obtain time-courses of expression levels is provided by microarray technology. However, the proper way of analyzing the resulting time course data is still very much an issue under investigation. The inherent time dependencies in the data suggest that clustering techniques which reflect those dependencies yield improved performance.
- Publication
Bioinformatics (Oxford, England), 2003, Vol 19 Suppl 1, pi255
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btg1036