We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Redundancy based detection of sequence polymorphisms in expressed sequence tag data using autoSNP.
- Authors
Barker, Gary; Batley, Jacqueline; O' Sullivan, Helen; Edwards, Keith J; Edwards, David
- Abstract
AutoSNP is a program to detect single nucleotide polymorphisms (SNPs) and insertion/deletion polymorphisms (indels) in expressed sequence tag (EST) data. The program uses d2cluster and cap3 to cluster and align EST sequences, and uses redundancy to differentiate between candidate SNPs and sequence errors. Candidate polymorphisms are identified as occurring in multiple reads within an alignment. For each candidate SNP, two measures of confidence are calculated, the redundancy of the polymorphism at a SNP locus and the co segregation of the candidate SNP with other SNPs in the alignment.
- Publication
Bioinformatics (Oxford, England), 2003, Vol 19, Issue 3, p421
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btf881