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- Title
Gene finding with a hidden Markov model of genome structure and evolution.
- Authors
Pedersen, Jakob Skou; Hein, Jotun
- Abstract
A growing number of genomes are sequenced. The differences in evolutionary pattern between functional regions can thus be observed genome-wide in a whole set of organisms. The diverse evolutionary pattern of different functional regions can be exploited in the process of genomic annotation. The modelling of evolution by the existing comparative gene finders leaves room for improvement.
- Publication
Bioinformatics (Oxford, England), 2003, Vol 19, Issue 2, p219
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/19.2.219