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- Title
A similarity-based method for genome-wide prediction of disease-relevant human genes.
- Authors
Freudenberg, J; Propping, P
- Abstract
A method for prediction of disease relevant human genes from the phenotypic appearance of a query disease is presented. Diseases of known genetic origin are clustered according to their phenotypic similarity. Each cluster entry consists of a disease and its underlying disease gene. Potential disease genes from the human genome are scored by their functional similarity to known disease genes in these clusters, which are phenotypically similar to the query disease.
- Publication
Bioinformatics (Oxford, England), 2002, Vol 18 Suppl 2, pS110
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/18.suppl_2.s110