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- Title
Multiple genome rearrangement: a general approach via the evolutionary genome graph.
- Authors
Korkin, Dmitry; Goldfarb, Lev
- Abstract
In spite of a well-known fact that genome rearrangements are supposed to be viewed in the light of the evolutionary relationships within and between the species involved, no formal underlying framework based on the evolutionary considerations for treating the questions arising in the area has been proposed. If such an underlying framework is provided, all the basic questions in the area can be posed in a biologically more appropriate and useful form: e.g., the similarity between two genomes can then be computed via the nearest ancestor, rather than 'directly', ignoring the evolutionary connections.
- Publication
Bioinformatics (Oxford, England), 2002, Vol 18 Suppl 1, pS303
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/18.suppl_1.s303