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- Title
Retrieval and on-the-fly alignment of sequence fragments from the HIV database.
- Authors
Gaschen, B; Kuiken, C; Korber, B; Foley, B
- Abstract
The amount of HIV-1 sequence data generated (presently around 42000 sequences, of which more than 22000 are from the V3 region of the viral envelope) presents a challenge for anyone working on the analysis of these data. A major problem is obtaining the region of interest from the stored sequences, which often contain but are not limited to that region. In addition, multiple alignment programs generally cannot deal with the large numbers of sequences that are available for many HIV-1 regions. We set out to provide our users with a tool that will retrieve and create an initial alignment of the HIV sequences that are available for a given genomic region.
- Publication
Bioinformatics (Oxford, England), 2001, Vol 17, Issue 5, p415
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/17.5.415