We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
MELTING, computing the melting temperature of nucleic acid duplex.
- Authors
Le Novère, N
- Abstract
MELTING computes the enthalpy and entropy of an oligonucleotide duplex helix-coil transition, and then its melting temperature. The program uses the method of nearest-neighbours. The set of thermodynamic parameters can be easily customized. The program provides several correction methods for the concentration of salt. MELTING is a free program, available at no cost and open-source. Perl scripts are provided to show how MELTING can be used to construct more ambitious programs.
- Publication
Bioinformatics (Oxford, England), 2001, Vol 17, Issue 12, p1226
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/17.12.1226