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- Title
Modeling and predicting transcriptional units of Escherichia coli genes using hidden Markov models.
- Authors
Yada, T; Nakao, M; Totoki, Y; Nakai, K
- Abstract
The hidden Markov model (HMM) is a valuable technique for gene-finding, especially because its flexibility enables the inclusion of various sequence features. Recent programs for bacterial gene-finding include the information of ribosomal binding site (RBS) to improve the recognition accuracy of the start codon, using this feature. We report here our attempt to extend the model into the total transcriptional unit, enabling the prediction of operon structures.
- Publication
Bioinformatics (Oxford, England), 1999, Vol 15, Issue 12, p987
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/15.12.987