We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Hidden Markov models for detecting remote protein homologies.
- Authors
Karplus, K; Barrett, C; Hughey, R
- Abstract
A new hidden Markov model method (SAM-T98) for finding remote homologs of protein sequences is described and evaluated. The method begins with a single target sequence and iteratively builds a hidden Markov model (HMM) from the sequence and homologs found using the HMM for database search. SAM-T98 is also used to construct model libraries automatically from sequences in structural databases.
- Publication
Bioinformatics (Oxford, England), 1998, Vol 14, Issue 10, p846
- ISSN
1367-4803
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/14.10.846