We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Base-calling for next-generation sequencing platforms.
- Authors
Ledergerber, Christian; Dessimoz, Christophe
- Abstract
Next-generation sequencing platforms are dramatically reducing the cost of DNA sequencing. With these technologies, bases are inferred from light intensity signals, a process commonly referred to as base-calling. Thus, understanding and improving the quality of sequence data generated using these approaches are of high interest. Recently, a number of papers have characterized the biases associated with base-calling and proposed methodological improvements. In this review, we summarize recent development of base-calling approaches for the Illumina and Roche 454 sequencing platforms.
- Publication
Briefings in bioinformatics, 2011, Vol 12, Issue 5, p489
- ISSN
1477-4054
- Publication type
Journal Article
- DOI
10.1093/bib/bbq077