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- Title
Growth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer.
- Authors
Nadler, Y; González, A M; Camp, R L; Rimm, D L; Kluger, H M; Kluger, Y
- Abstract
Growth factor receptor-bound protein-7 (Grb7) is an adapter-type signaling protein recruited to various tyrosine kinases, including HER2/neu. Grb7-specific inhibitors are in early development. As with other targeted therapies, response to therapy might be associated with target expression.
- Publication
Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Vol 21, Issue 3, p466
- ISSN
1569-8041
- Publication type
Journal Article
- DOI
10.1093/annonc/mdp346