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Title
HSP90 as a marker of progression in melanoma.
Authors
McCarthy, M M; Pick, E; Kluger, Y; Gould-Rothberg, B; Lazova, R; Camp, R L; Rimm, D L; Kluger, H M
Abstract
HSP90 chaperones molecules critical for cell survival and malignant progression, including mutated B-raf. HSP90-targeting agents are in clinical trials. No large studies have been conducted on expression of HSP90 in melanomas.
Publication
Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Vol 19, Issue 3, p590