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- Title
A phase II study of epigenetic therapy with hydralazine and magnesium valproate to overcome chemotherapy resistance in refractory solid tumors.
- Authors
Candelaria, M; Gallardo-Rincón, D; Arce, C; Cetina, L; Aguilar-Ponce, J L; Arrieta, O; González-Fierro, A; Chávez-Blanco, A; de la Cruz-Hernández, E; Camargo, M F; Trejo-Becerril, C; Pérez-Cárdenas, E; Pérez-Plasencia, C; Taja-Chayeb, L; Wegman-Ostrosky, T; Revilla-Vazquez, A; Dueñas-González, A
- Abstract
Epigenetic aberrations lead to chemotherapy resistance; hence, their reversal by inhibitors of DNA methylation and histone deacetylases may overcome it.
- Publication
Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Vol 18, Issue 9, p1529
- ISSN
0923-7534
- Publication type
Journal Article
- DOI
10.1093/annonc/mdm204