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- Title
Automated quantitative analysis of DCC tumor suppressor protein in ovarian cancer tissue microarray shows association with beta-catenin levels and outcome in patients with epithelial ovarian cancer.
- Authors
Bamias, A; Yu, Z; Weinberger, P M; Markakis, S; Kowalski, D; Camp, R L; Rimm, D L; Dimopoulos, M A; Psyrri, A
- Abstract
The deleted in colorectal cancer (DCC) protein, the product of DCC tumor suppressor gene, is frequently altered in cancer. Preclinical data demonstrate that DCC regulates beta-catenin levels. Here, we sought to determine the association of DCC with beta-catenin protein levels, clinicopathological parameters and patient outcome in ovarian cancer using a method of in situ compartmentalized protein analysis.
- Publication
Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Vol 17, Issue 12, p1797
- ISSN
0923-7534
- Publication type
Journal Article
- DOI
10.1093/annonc/mdl310