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- Title
ERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabine.
- Authors
Ceppi, P; Volante, M; Novello, S; Rapa, I; Danenberg, K D; Danenberg, P V; Cambieri, A; Selvaggi, G; Saviozzi, S; Calogero, R; Papotti, M; Scagliotti, G V
- Abstract
Pivotal studies indicate a role of excision repair cross-complementation 1 (ERCC1) gene and ribonucleotide reductase M1 (RRM1) gene in conferring a differential sensitivity to cytotoxic chemotherapy and epidermal growth factor receptor (EGFR) gene has been recently extensively investigated in non-small-cell lung cancer (NSCLC).
- Publication
Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Vol 17, Issue 12, p1818
- ISSN
0923-7534
- Publication type
Journal Article
- DOI
10.1093/annonc/mdl300