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- Title
Insulin-like growth factor receptor 1 (IGFR-1) is significantly associated with longer survival in non-small-cell lung cancer patients treated with gefitinib.
- Authors
Cappuzzo, F; Toschi, L; Tallini, G; Ceresoli, G L; Domenichini, I; Bartolini, S; Finocchiaro, G; Magrini, E; Metro, G; Cancellieri, A; Trisolini, R; Crino, L; Bunn, P A, Jr; Santoro, A; Franklin, W A; Varella-Garcia, M; Hirsch, F R
- Abstract
The aim of the study was to assess whether loss of PTEN and expression of insulin-like growth factor receptor 1 (IGFR-1) could be responsible for intrinsic resistance to the tyrosine kinase inhibitor (TKI) gefitinib.
- Publication
Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Vol 17, Issue 7, p1120
- ISSN
0923-7534
- Publication type
Journal Article
- DOI
10.1093/annonc/mdl077