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- Title
Expression of Cox-2 protein in radioresistant laryngeal cancer.
- Authors
Nix, P; Lind, M; Greenman, J; Stafford, N; Cawkwell, L
- Abstract
Radiotherapy is the principal modality used to treat early stage laryngeal cancer. Unfortunately treatment failures occur in 10-25% of patients. Subsequent salvage surgery is technically more difficult, with increased complication and failure rates. The ability to predict or prevent radioresistance would improve the poor survival associated with this disease. Cox-2 is an inducible enzyme involved with prostaglandin synthesis. We investigated a potential role for Cox-2 in predicting radioresistance in laryngeal cancer.
- Publication
Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Vol 15, Issue 5, p797
- ISSN
0923-7534
- Publication type
Journal Article
- DOI
10.1093/annonc/mdh185