We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Alcohol intake after serotonin transporter inactivation in mice.
- Authors
Kelaï, Sabah; Aïssi, Franck; Lesch, Klaus Peter; Cohen-Salmon, Charles; Hamon, Michel; Lanfumey, Laurence
- Abstract
Knock-out mice lacking the serotonin transporter [5-hydroxytryptamine transporter (5-HTT)] were used to assess the influence of 5-HT re-uptake on ethanol consumption. Under a free-choice paradigm, alcohol intake was lower in mutant than in wild-type mice, and pharmacological blockade of 5-HTT by fluoxetine reduced alcohol intake in wild-type mice only. These data confirm the inhibitory effect of 5-HTT inactivation on ethanol intake.
- Publication
Alcohol and alcoholism (Oxford, Oxfordshire), 2003, Vol 38, Issue 4, p386
- ISSN
0735-0414
- Publication type
Journal Article
- DOI
10.1093/alcalc/agg095