We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Assessment of iron status of Zairean women of childbearing age by serum transferrin receptor.
- Authors
Kuvibidila, S; Yu, L C; Ode, D L; Warrier, R P; Mbele, V
- Abstract
Soluble transferrin receptor (sTfR), previously shown to be a sensitive indicator of tissue iron deficiency, was used to assess iron status of 104 Zairean women (69 lactating, 19 pregnant, and 16 nonpregnant, nonlactating women). Thirteen iron-sufficient female laboratory employees were also studied. Mean sTfR concentrations were higher in pregnant women (9.90 mg/L) than in lactating women (8.55 mg/L), nonlactating women (7.74 mg/L), and laboratory employees (5.11 mg/L) (P < 0.005). Mean serum ferritin and transferrin saturation were lower in pregnant than nonpregnant women. sTfR negatively correlated with hemoglobin (P < 0.05) and transferrin saturation (P < 0.05), and nonsignificantly with ferritin and transferrin. With 7.26 mg sTfR/L (the upper limit of laboratory employees) as the cutoff value, sTfR identified 67% of women with tissue iron deficiency compared with 11.5-57% for transferrin saturation, hemoglobin, or ferritin. Despite the moderate sensitivity (68.5%), 90% of women with sTfR > 7.26 mg/L also had another index below normal and 54% had serum ferritin < or = 50 micrograms/L.
- Publication
The American journal of clinical nutrition, 1994, Vol 60, Issue 4, p603
- ISSN
0002-9165
- Publication type
Journal Article
- DOI
10.1093/ajcn/60.4.603