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- Title
Biological determinants of immune reconstitution in HIV-infected patients receiving antiretroviral therapy: the role of interleukin 7 and interleukin 7 receptor α and microbial translocation.
- Authors
Rajasuriar, Reena; Booth, David; Solomon, Ajantha; Chua, Kyra; Spelman, Tim; Gouillou, Maelenn; Schlub, Timothy E; Davenport, Miles; Crowe, Suzanne; Elliott, Julian; Hoy, Jennifer; Fairley, Christopher; Stewart, Graeme; Cameron, Paul; Lewin, Sharon R
- Abstract
Multiple host factors may influence CD4(+) T cell reconstitution in human immunodeficiency virus (HIV)-infected patients after suppressive antiretroviral therapy (ART). We hypothesized that residual immune activation and polymorphisms in the interleukin 7 (IL-7) receptor α (IL-7Rα) gene were important for immune recovery.
- Publication
The Journal of infectious diseases, 2010, Vol 202, Issue 8, p1254
- ISSN
1537-6613
- Publication type
Journal Article
- DOI
10.1086/656369