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Title
Paucity of initial cerebrospinal fluid inflammation in cryptococcal meningitis is associated with subsequent immune reconstitution inflammatory syndrome.
Authors
Boulware, David R; Bonham, Shulamith C; Meya, David B; Wiesner, Darin L; Park, Gregory S; Kambugu, Andrew; Janoff, Edward N; Bohjanen, Paul R
Abstract
Cryptococcal meningitis (CM)-related immune reconstitution inflammatory syndrome (IRIS) complicates antiretroviral therapy (ART) in 20%-40% of ART-naive persons with AIDS and prior CM. Pathogenesis is unknown.
Publication
The Journal of infectious diseases, 2010, Vol 202, Issue 6, p962