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- Title
Treatment outcomes among patients with extensively drug-resistant tuberculosis: systematic review and meta-analysis.
- Authors
Jacobson, Karen R; Tierney, Dylan B; Jeon, Christie Y; Mitnick, Carole D; Murray, Megan B
- Abstract
. The treatment of extensively drug-resistant tuberculosis (XDR TB) presents a major challenge. Second-line antimycobacterial drugs are less effective, more toxic, and more costly than first-line agents, and XDR TB strains are, by definition, resistant to the most potent second-line options: the injectable agents and fluoroquinolones. We conducted a meta-analysis to assess XDR TB treatment outcomes and to identify therapeutic approaches associated with favorable responses.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Vol 51, Issue 1, p6
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/653115