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- Title
Rapid selection of oseltamivir- and peramivir-resistant pandemic H1N1 virus during therapy in 2 immunocompromised hosts.
- Authors
Memoli, Matthew J; Hrabal, Rachel J; Hassantoufighi, Arash; Eichelberger, Maryna C; Taubenberger, Jeffery K
- Abstract
Pandemic 2009 H1N1 virus isolates containing the neuraminidase inhibitor resistance mutation H275Y have been reported. We describe rapid selection for the H275Y resistance mutation during therapy in 2 immunocompromised individuals at 9 and 14 days of therapy, as well as the first described case of clinically significant resistance to peramivir.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Vol 50, Issue 9, p1252
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/651605